Jarrow Formulas SAMe provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. SAMe 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains More of the Active S,S Form.
Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMeis a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas®SAMe is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAMe, the highest active level available.
SAMe supports the production of healthy connective tissue through transulfuration.* In this process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.*
Brain Metabolism and Mood*
SAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membraners and precursor to acetylcholine, as well as neurotransmitters such dopamine, norepinephrine, and serotonin, and has been shown to have a positive effect on mood.*
SAMe metabolism supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification.*
|Serving Size 1 Tablet|
|Amount Per Serving||% DV|
|S-Adenosyl Methionine||200 mg||†|
|(from 400 mg of SAMe Tosylate Disulfate)|
|† Daily Value (DV) not established.|
Cellulose, mannitol, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, sodium starch glycolate, enteric coating (modified cellulose, magnesium silicate, triethyl citrate and riboflavin).
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, or peanuts/tree nuts.
EnteroGuard® is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.
Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.
WARNING: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using this product. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAMe. Do not use if pregnant or nursing. Do not exceed recommended intake. May cause gastrointestinal upset in some persons. Consult a healthcare professional before using this product if you are trying to conceive, under the age of 18, or have a medical condition; if adverse reactions occur, discontinue use.
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